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As a consequence of its enriched G content, The only-stranded telomere G overhangs can type G-quadruplexes, wherever each G foundation serves as both donor and acceptor for hydrogen bond development. In human, telomeric G-quadruplex structures have been implicated in telomere defense, suppression of recombination, and inhibition of telomerase-depen

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Manhattan plot of altered log10 (P values) for all phecodes evaluating their event for each SD telomere shortening. Highlighted are associations results with ?log10 P values concerning 10 and one hundred twenty.Cells with limitless proliferative ability – notably stem cells and cancer cells – need to activate a telomere lengthening system. Ther

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